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Peptide record

TPDB08271

Antibacterial Anticancer Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08271
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard-residue multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
DKERPICSNTFRGRKC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C78H132N28O24S2
AQHLMWYV
R
1910.20
9.92
5
2
2
+3
4.54
-1.437
24.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
125
0.07
5
Residue Composition
number
0
A
3
R
1
N
1
D
2
C
1
E
0
Q
1
G
0
H
1
I
0
L
2
K
0
M
1
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 2 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 2 M: 0 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
16 reviewed residue count
C78H132N28O24S2 sequence-only estimate (linear, free termini)
1910.20 sequence-only estimate (linear, free termini)
9.92 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
4.54 sequence-only estimate (linear, free termini)
-1.437 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

3.8% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
3.8% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion. | Peptides | 2019