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Peptide record

TPDB08264

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08264
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GVVVRWGRVWVRGVRR
Physicochemical Analysis
C88H145N33O17
ANDCEQHILKMFPSTY
V
1937.33
13.00
5
0
8
+5
0.80
-0.019
108.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
567.79
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
6
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 6
Chemical Descriptors
16
C88H145N33O17
1937.33
13.00
+5
0.80
-0.019
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
5% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell selectivity and interaction with model membranes of Val/Arg-rich peptides. | J Pept Sci | 2011
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Biochemical property and in vivo efficacies of novel Val/Arg-rich antimicrobial peptide. | Protein Pept Lett | 2012