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Peptide record

TPDB08261

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08261
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GVVVRVARVVVRWVRR
Physicochemical Analysis
C86H152N32O17
NDCEQHILKMFPSTY
V
1906.36
13.00
5
0
10
+5
2.60
0.725
151.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
288.51
0
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
8
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 8
Chemical Descriptors
16
C86H152N32O17
1906.36
13.00
+5
2.60
0.725
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
50% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of Val/Arg-rich peptides: effects of net charge and pro on activity. | Chem Biol Drug Des | 2014