Back to search

Peptide record

TPDB08226

Antibacterial Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08226
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 16-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KVLSKVHTLLKAVLAL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C82H149N21O19
RNDCEQGIMFPWY
L
1733.21
10.84
4
0
10
+3
-0.82
1.175
188.75
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
5
L
3
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 5 K: 3 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
16 reviewed residue count
C82H149N21O19 sequence-only estimate (linear, free termini)
1733.21 sequence-only estimate (linear, free termini)
10.84 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
-0.82 sequence-only estimate (linear, free termini)
1.175 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
1-16 µM
Hemolytic Cytotoxic
0% Hemolysis | 1-16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 2 Activity

Activity

2.41±0.98% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
2.41±0.98% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 3 Activity

Activity

10.28±4.3% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
10.28±4.3% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 4 Activity

Activity

23.10±3.41% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
23.10±3.41% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017