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Peptide record

TPDB08214

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08214
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
TSFLNELNKYNEKKFI
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C92H142N22O27
ARDCQGHMPWV
NK
1988.27
9.58
3
2
6
+1
2.22
-0.894
73.12
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
0.75
6
Residue Composition
number
0
A
0
R
3
N
0
D
0
C
2
E
0
Q
0
G
0
H
1
I
2
L
3
K
0
M
2
F
0
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 3 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 3 M: 0 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
16 reviewed residue count
C92H142N22O27 sequence-only estimate (linear, free termini)
1988.27 sequence-only estimate (linear, free termini)
9.58 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
2.22 sequence-only estimate (linear, free termini)
-0.894 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Four novel antimicrobial peptides derived from human C8?-MACPF | Biotechnol Lett | 2014