Peptide record

TPDB08170

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08170
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
CVHWQTNTARTSCIGP
Physicochemical Analysis
C74H116N24O23S2
DELKMFY
T
1774.00
8.30
2
0
4
+1
1.04
-0.312
48.75
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
317.08
8
Residue Composition
number
1
A
1
R
1
N
0
D
2
C
0
E
1
Q
1
G
1
H
1
I
0
L
0
K
0
M
0
F
1
P
1
S
3
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 3 W: 1 Y: 0 V: 1
Chemical Descriptors
16
C74H116N24O23S2
1774.00
8.30
+1
1.04
-0.312
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
55 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. subtilis (MIC 55 ug/ml). Activity against other bacteria and fungi were not detected till 100 ug/ml. Updated 7/20
Evidence 2 Activity

Activity

MIC
Antifungal
55 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. subtilis (MIC 55 ug/ml). Activity against other bacteria and fungi were not detected till 100 ug/ml. Updated 7/20
Evidence 3 Activity

Activity

MIC
Antiparasitic
55 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against B. subtilis (MIC 55 ug/ml). Activity against other bacteria and fungi were not detected till 100 ug/ml. Updated 7/20
Evidence 4 Activity

Activity

MIC
Antiviral
55 µg/mL

Target

B. subtilis

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against B. subtilis (MIC 55 ug/ml). Activity against other bacteria and fungi were not detected till 100 ug/ml. Updated 7/20
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 6 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Rat mast cells

Target

Rat mast cells

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010