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Peptide record

TPDB08168

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08168
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
DCTRWIIGINGRICRD
Physicochemical Analysis
C79H131N27O23S2
AEQHLKMFPSYV
I
1891.20
8.30
3
2
5
+1
1.90
-0.213
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5625
297.43
4
Residue Composition
number
0
A
3
R
1
N
2
D
2
C
0
E
0
Q
2
G
0
H
4
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 2 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C79H131N27O23S2
1891.20
8.30
+1
1.90
-0.213
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 2 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 3 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 4 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 5 Activity

Activity

MIC
Antiparasitic
18.75 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 6 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 7 Activity

Activity

MIC
Antiviral
18.75 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 8 Activity

Activity

MIC
Antiviral
75 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

Active against S. aureus ATCC25923 (MIC 18.75 ug/ml) and C. albicans ATCC2002 (MIC 75 ug/ml). 7.6% poor Hemolysis at 100 ug/ml. Updated 7/2020
Evidence 9 Activity

Activity

8% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 10 Activity

Activity

(8.87±1.63)% Degranulation
Toxicity
50 µg/mL
Cytotoxic
(8.87±1.63)% Degranulation | 50 | µg/mL | target cell: Rat mast cells

Target

Rat mast cells

Source & Reference

NA
DBAASP
Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata | Genomics | 2010
Evidence 11 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19778602]7.62±1.6% hemolytic activity at 100 µg/ml against rabbit red cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Genomics. 2010 Jan 95(1):66-71.