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Peptide record

TPDB08159

Antibacterial Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08159
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KALWKTMLKKLGTMAL
Physicochemical Analysis
C85H149N21O19S2
RNDCEQHIFPSYV
LK
1833.37
11.00
4
0
9
+4
-0.64
0.269
110.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
299.99
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
4
K
2
M
0
F
0
P
0
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 4 M: 2 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C85H149N21O19S2
1833.37
11.00
+4
-0.64
0.269
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and antimicrobial activity of dermaseptin S1 analogues. | Bioorg Med Chem | 2008