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Peptide record

TPDB08136

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB08136
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLKKLISWIKRAAQQG
Physicochemical Analysis
C82H141N25O20
NDCEHMFPTYV
K
1797.18
11.73
4
0
7
+4
1.16
-0.344
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
306.04
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
2
I
2
L
3
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 2 L: 2 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C82H141N25O20
1797.18
11.73
+4
1.16
-0.344
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 100 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Biological activities of C-terminal 15-residue synthetic fragment of melittin: design of an analog with improved antibacterial activity. | FEBS Lett | 1999