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Peptide record

TPDB08134

Antibacterial Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08134
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
AGLQFPVGRIGRLLRK
Physicochemical Analysis
C81H141N27O18
NDCEHMSTWY
RGL
1781.18
12.71
4
0
7
+4
1.26
0.062
121.88
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
3
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C81H141N27O18
1781.18
12.71
+4
1.26
0.062
Evidence Records 19 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

E. faecium ATCC 19434

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ E. faecium ATCC 19434 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 AT
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Active against Gram+ E. faecium ATCC 19434 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi AT
Evidence 3 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

Escherichia coli O157 ATCC 43895

Source & Reference

dbAMP

Other

4 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant st
Evidence 4 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

S. typhi ATCC 19430

Source & Reference

dbAMP

Other

(MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi
Evidence 5 Activity

Activity

MIC
Antibacterial
6.3-12.5 µM

Target

Pseudomonas aeruginosa ATCC 27853 including three resistant strains

Source & Reference

dbAMP

Other

, Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM),
Evidence 6 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

Candida albicans ATCC 90028

Source & Reference

dbAMP

Other

, P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rub
Evidence 7 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C. parapsilosis ATCC 22019

Source & Reference

dbAMP

Other

three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

T. beigelii KCTC 7707

Source & Reference

dbAMP

Other

and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 9 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

T. rubrum KCTC 6345

Source & Reference

dbAMP

Other

.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µM

Target

E. faecium ATCC 19434

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ E. faecium ATCC 19434 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 AT
Evidence 11 Activity

Activity

MIC
Antifungal
25 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ E. faecium ATCC 19434 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi AT
Evidence 12 Activity

Activity

MIC
Antifungal
6.3 µM

Target

Escherichia coli O157 ATCC 43895

Source & Reference

dbAMP CAFPdb Antifungipept

Other

4 (MIC 12.5 uM), S. aureus ATCC 25923 (MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant st
Evidence 13 Activity

Activity

MIC
Antifungal
12.5 µM

Target

S. typhi ATCC 19430

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 25 uM), and MRSA (MIC 12.5 uM), Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi
Evidence 14 Activity

Activity

MIC
Antifungal
6.3-12.5 µM

Target

Pseudomonas aeruginosa ATCC 27853 including three resistant strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, Gram- bacteria E. coli O157 ATCC 43895 (MIC 6.3 uM), S. typhi ATCC 19430 (MIC 12.5 uM), P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM),
Evidence 15 Activity

Activity

MIC
Antifungal
6.3 µM

Target

Candida albicans ATCC 90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, P. aeruginosa ATCC 27853 including three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rub
Evidence 16 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C. parapsilosis ATCC 22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

three resistant strains (MIC 6.3-12.5 uM), and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 17 Activity

Activity

MIC
Antifungal
6.3 µM

Target

T. beigelii KCTC 7707

Source & Reference

dbAMP CAFPdb Antifungipept

Other

and fungi C. albicans ATCC 90028 (MIC 6.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 18 Activity

Activity

MIC
Antifungal
6.3 µM

Target

T. rubrum KCTC 6345

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.3 uM), C. parapsilosis ATCC 22019 (MIC 12.5 uM), T. beigelii KCTC 7707 (MIC 6.3 uM), and T. rubrum KCTC 6345 (MIC 6.3 uM).
Evidence 19 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Scolopendin 2, a cationic antimicrobial peptide from centipede, and its membrane-active mechanism. | Biochim Biophys Acta | 2015