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Peptide record

TPDB08127

Antibacterial Antifungal Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08127
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KFWPWKIFCAITKKC
Physicochemical Analysis
C94H139N21O17S2
RNDEQGHLMSYV
K
1899.39
10.17
4
0
7
+4
-2.68
0.113
58.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11125
585.71
3
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
0
L
4
K
0
M
2
F
1
P
0
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 4 M: 0 F: 2 P: 1 S: 0 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
15
C94H139N21O17S2
1899.39
10.17
+4
-2.68
0.113
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
32.07 µM
Hemolytic Cytotoxic
10% Hemolysis | 32.07 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy | Biology (Basel) | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis