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Peptide record

TPDB08124

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08124
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
IWLTALKFLGKNLGK
Physicochemical Analysis
C83H136N20O18
RDCEQHMPSYV
L
1702.12
10.84
3
0
8
+3
-2.15
0.447
136.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
323.13
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
4
L
3
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 3 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C83H136N20O18
1702.12
10.84
+3
-2.15
0.447
Evidence Records 2 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
48.06 µM
Hemolytic Cytotoxic
1% Hemolysis | 48.06 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment. | Exp Biol Med (Maywood) | 2021
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
381.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 381.4 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment. | Exp Biol Med (Maywood) | 2021