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Peptide record

TPDB08122

Antibacterial Anticancer Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08122
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
AKKKLSRWWLRWWVK
Physicochemical Analysis
C103H155N29O17
NDCEQGHIMFPTY
KW
2071.55
12.44
6
0
8
+6
-2.91
-1.027
78.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
22000
1062.01
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
4
K
0
M
0
F
0
P
1
S
0
T
4
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 4 M: 0 F: 0 P: 0 S: 1 T: 0 W: 4 Y: 0 V: 1
Chemical Descriptors
15
C103H155N29O17
2071.55
12.44
+6
-2.91
-1.027
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
<200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A small mycobacteriophage-derived peptide and its improved isomer restrict mycobacterial infection via dual mycobactericidal-immunoregulatory activities. | J Biol Chem | 2019
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
<200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
A small mycobacteriophage-derived peptide and its improved isomer restrict mycobacterial infection via dual mycobactericidal-immunoregulatory activities. | J Biol Chem | 2019
Evidence 3 Activity

Activity

0% Cytotoxicity
Toxicity
<200 µg/mL
Cytotoxic
0% Cytotoxicity | <200 | µg/mL | target cell: Murine peritoneal macrophages

Target

Murine peritoneal macrophages

Source & Reference

NA
DBAASP
A small mycobacteriophage-derived peptide and its improved isomer restrict mycobacterial infection via dual mycobactericidal-immunoregulatory activities. | J Biol Chem | 2019
Evidence 4 Activity

Activity

0% Cytotoxicity
Toxicity
<200 µg/mL
Cytotoxic
0% Cytotoxicity | <200 | µg/mL | target cell: Vero E6 cells

Target

Vero E6 cells

Source & Reference

NA
DBAASP
A small mycobacteriophage-derived peptide and its improved isomer restrict mycobacterial infection via dual mycobactericidal-immunoregulatory activities. | J Biol Chem | 2019