Back to search

Peptide record

TPDB08114

Antibacterial Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08114
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
VAIALKAAAYHTHKE
Physicochemical Analysis
C74H119N21O20
RNDCQGMFPSW
A
1622.89
9.65
4
1
9
+1
3.47
0.120
104.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
91.81
2
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
2
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 2 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C74H119N21O20
1622.89
9.65
+1
3.47
0.120
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

Candida albicans 10231

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
not active. At pH 5.4, the peptide and its zinc and copper complexes were active against C. albicans 10231 (MIC 1 ug/ml). Zn2+ or Cu2+ has little effect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.fae
Evidence 2 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

Enterococcus faecalis 29212

Source & Reference

dbAMP

Other

g/ml). Zn2+ or Cu2+ has little effect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.faecalis 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.aureus 29212

Source & Reference

dbAMP

Other

ect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.faecalis 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 1
Evidence 4 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

K.pneumoniae 13883

Source & Reference

dbAMP

Other

s 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was obser
Evidence 5 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

P.aeruginosa 15442

Source & Reference

dbAMP

Other

MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was observed against S. aureus (MIC 64 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

ginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was observed against S. aureus (MIC 64 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

Candida albicans 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
not active. At pH 5.4, the peptide and its zinc and copper complexes were active against C. albicans 10231 (MIC 1 ug/ml). Zn2+ or Cu2+ has little effect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.fae
Evidence 8 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

Enterococcus faecalis 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

g/ml). Zn2+ or Cu2+ has little effect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.faecalis 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC
Evidence 9 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

S.aureus 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ect on antifungal activity (MIC 0.5-2 ug/ml). Inactive: E.faecalis 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 1
Evidence 10 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

K.pneumoniae 13883

Source & Reference

dbAMP CAFPdb Antifungipept

Other

s 29212 (MIC>128 ug/ml), S.aureus 29212 (MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was obser
Evidence 11 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

P.aeruginosa 15442

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC>128 ug/ml), E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was observed against S. aureus (MIC 64 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ginosa 15442 (MIC>128 ug/ml). In the presence of Zn2+, weak activity was observed against S. aureus (MIC 64 ug/ml).