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Peptide record

TPDB08079

Antibacterial Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08079
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia HemoPI Hemolytic2
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VNWKKSLGKSIKVVK
Physicochemical Analysis
C80H140N22O19
ARDCEQHMFPTY
K
1714.13
11.12
5
0
6
+5
3.13
-0.333
110.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
320.86
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
5
K
0
M
0
F
0
P
2
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
15
C80H140N22O19
1714.13
11.12
+5
3.13
-0.333
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
Hemolysis
31.3 µM
[Ref.22526241]LC50=31.3 µM against human red blood cells

Target

human red blood cells

Source & Reference

NA
DRAMP4
Amino Acids. 2012 Nov 43(5):2047-58.
Evidence 2 Activity

Activity

LC50
Toxicity
31.3 µM
Hemolytic
Hemolytic_activity: [Ref.22526241]LC50=31.3 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2012 Nov 43(5):2047-58.
Evidence 3 Hemolysis

Activity

31.3 µM
LC50
[Ref.22526241]LC50=31.3 µM against human red blood cells
Hemolysis

Target

human red blood cells

Source & Reference

HemoPI
Amino Acids. 2012 Nov 43(5):2047-58.
DRAMP4
NA