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Peptide record

TPDB08074

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08074
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VAIALKAAHYHTHKE
Physicochemical Analysis
C77H121N23O20
RNDCQGMFPSW
A
1688.95
9.65
5
1
8
+1
4.60
-0.213
98.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
88.22
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
3
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 3 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C77H121N23O20
1688.95
9.65
+1
4.60
-0.213
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
pH-sensitive: At pH 7.4, it was not active. At pH 5.4, the peptide was active against E. coli, P. aeruginosa, and C. albicans but not S.aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
pH-sensitive: At pH 7.4, it was not active. At pH 5.4, the peptide was active against E. coli, P. aeruginosa, and C. albicans but not S.aureus.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

pH-sensitive: At pH 7.4, it was not active. At pH 5.4, the peptide was active against E. coli, P. aeruginosa, and C. albicans but not S.aureus.
Evidence 4 Activity

Activity

1% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
1% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010