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Peptide record

TPDB08066

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08066
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GTKRGKLCRISRLAL
Physicochemical Analysis
C71H134N26O18S1
NDEQHMFPWYV
RL
1672.07
12.13
5
0
5
+5
2.30
-0.227
110.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
3
R
0
N
0
D
1
C
0
E
0
Q
2
G
0
H
1
I
3
L
2
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C71H134N26O18S1
1672.07
12.13
+5
2.30
-0.227
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 32 ug/ml). Warning: the mature sequence may differ from
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 32 ug/ml). Warning: the mature sequence may differ from the synthetic peptide used here. Link updat
Evidence 3 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 32 ug/ml). Warning: the mature sequence may differ from
Evidence 4 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 32 ug/ml). Warning: the mature sequence may differ from the synthetic peptide used here. Link updat
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016