Back to search

Peptide record

TPDB08049

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08049
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF dbAMP 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWKLFKKGIGAVLKV
Physicochemical Analysis
C85H143N21O16
RNDCEQHMPSTY
K
1715.20
11.12
5
0
8
+5
0.53
0.260
123.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
320.66
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
15
C85H143N21O16
1715.20
11.12
+5
0.53
0.260
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Antibacterial
7.0 µM

Target

P. falciparum

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
0.8 uM), S. aureus Cowan 1 (LC 29 uM), and S. pyogenes (LC 0.7 uM). Antimalarial activity:P. falciparum (IC50 7.0 uM).
Evidence 2 Activity

Activity

IC50
Antifungal
7.0 µM

Target

P. falciparum

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
0.8 uM), S. aureus Cowan 1 (LC 29 uM), and S. pyogenes (LC 0.7 uM). Antimalarial activity:P. falciparum (IC50 7.0 uM).
Evidence 3 Activity

Activity

IC50
Antiparasitic
7.0 µM

Target

P. falciparum

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
0.8 uM), S. aureus Cowan 1 (LC 29 uM), and S. pyogenes (LC 0.7 uM). Antimalarial activity:P. falciparum (IC50 7.0 uM).