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Peptide record

TPDB08035

Antibacterial Antifungal Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB08035
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRGWVLALYLRYGRR
Physicochemical Analysis
C89H143N31O18
NDCEQHIKMFPST
R
1935.31
12.23
5
0
8
+5
-1.44
-0.627
104.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
438.17
2
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
15
C89H143N31O18
1935.31
12.23
+5
-1.44
-0.627
Evidence Records 3 records
Evidence 1 Activity

Activity

23% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
23% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity | J Am Chem Soc | 2009
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
0% Hemolysis | 15 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity | J Am Chem Soc | 2009
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis