TPDB

3D PDB MODEL

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TPDB ID TPDB07978

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

AntiBP3 Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 15-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.

Sequence

FKKLKKLFSKLFSFK

FASTA

>TPDB07978|Antibacterial|length=15
FKKLKKLFSKLFSFK

Formula C96H153N21O18

Absent Amino Acids ARNDCEQGHIMPTWYV

Common Amino Acids K

Mass 1889.40

PI 11.21

Basic Residues 6

Acidic Residues 0

Hydrophobic Residues 7

Net Charge +6

Boman Index 0.00

Hydrophobicity -0.160

Aliphatic Index 78.00

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

0

A

0

R

0

N

0

D

0

C

0

E

0

Q

0

G

0

H

0

I

3

L

6

K

0

M

4

F

0

P

2

S

0

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 6 M: 0 F: 4 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0

Length

15

Formula

C96H153N21O18

Mass

1889.40

PI

11.21

Net Charge

+6

Boman Index

0.00

Hydrophobicity

-0.160

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2 µM

Target

Target Organism Escherichia coli ATCC 25922

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- E. coli ATCC 25922 (MIC 2 uM), P. aeruginosa ATCC 27853 (MIC 2 uM), K. pneumoniae ATCC 700603 (MIC 2 uM), Gram+ S. aure

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2 µM

Target

Target Organism Pseudomonas aeruginosa ATCC 27853

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- E. coli ATCC 25922 (MIC 2 uM), P. aeruginosa ATCC 27853 (MIC 2 uM), K. pneumoniae ATCC 700603 (MIC 2 uM), Gram+ S. aureus ATCC 25923 (MIC 1 uM), S. epidermi

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2 µM

Target

Target Organism Klebsiella pneumoniae ATCC 700603

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- E. coli ATCC 25922 (MIC 2 uM), P. aeruginosa ATCC 27853 (MIC 2 uM), K. pneumoniae ATCC 700603 (MIC 2 uM), Gram+ S. aureus ATCC 25923 (MIC 1 uM), S. epidermidis ATCC 12228 (MIC 1 uM), S. pneumoni

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism Staphylococcus aureus ATCC 25923

Source & Reference

Database Source NA

Other

Evidence Text

C 2 uM), P. aeruginosa ATCC 27853 (MIC 2 uM), K. pneumoniae ATCC 700603 (MIC 2 uM), Gram+ S. aureus ATCC 25923 (MIC 1 uM), S. epidermidis ATCC 12228 (MIC 1 uM), S. pneumoniae ATCC 49619 (MIC 2 uM).

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism Staphylococcus epidermidis ATCC 12228

Source & Reference

Database Source NA

Other

Evidence Text

(MIC 2 uM), K. pneumoniae ATCC 700603 (MIC 2 uM), Gram+ S. aureus ATCC 25923 (MIC 1 uM), S. epidermidis ATCC 12228 (MIC 1 uM), S. pneumoniae ATCC 49619 (MIC 2 uM).

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2 µM

Target

Target Organism S. pneumoniae ATCC 49619

Source & Reference

Database Source NA

Other

Evidence Text

(MIC 2 uM), Gram+ S. aureus ATCC 25923 (MIC 1 uM), S. epidermidis ATCC 12228 (MIC 1 uM), S. pneumoniae ATCC 49619 (MIC 2 uM).