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Peptide record

TPDB07955

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07955
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ICLKKWPWWPWRRCK
Physicochemical Analysis
C102H148N28O16S2
ANDEQGHMFSTYV
W
2086.60
10.82
5
0
6
+5
-3.26
-0.947
52.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
22125
1060.34
2
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
1
L
3
K
0
M
0
F
2
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 0 F: 0 P: 2 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
15
C102H148N28O16S2
2086.60
10.82
+5
-3.26
-0.947
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-based design of an indolicidin peptide analogue with increased protease stability. | Biochemistry | 2003