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Peptide record

TPDB07948

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07948
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLPALISWIKRKRGG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C76H130N24O17
NDCEQHMFTYV
G
1652.02
12.42
4
0
6
+4
1.18
-0.193
110.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
3.33
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
2
L
2
K
0
M
0
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 2 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15 reviewed residue count
C76H130N24O17 sequence-only estimate (linear, free termini)
1652.02 sequence-only estimate (linear, free termini)
12.42 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
1.18 sequence-only estimate (linear, free termini)
-0.193 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Deletion of two C-terminal Gln residues of 12-26-residue fragment of melittin improves its antimicrobial activity. | Peptides | 2005