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Peptide record

TPDB07939

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07939
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FRRFRKWFRRFLKLF
Physicochemical Analysis
C110H163N33O16
ANDCEQGHIMPSTYV
RF
2203.72
13.01
7
0
8
+7
-2.59
-0.640
52.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
249.58
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
2
K
0
M
5
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 2 M: 0 F: 5 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C110H163N33O16
2203.72
13.01
+7
-2.59
-0.640
Evidence Records 1 records
Evidence 1 Activity

Activity

70% Hemolysis
Toxicity
60 µM
Hemolytic Cytotoxic
70% Hemolysis | 60 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of antimicrobial, cytotoxic, and antiendotoxin properties of short peptides with different hydrophobic amino acids at "a" and "d" positions of a heptad repeat sequence. | J Med Chem | 2013