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Peptide record

TPDB07935

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07935
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FRIRVRVKWKLFKKI
Physicochemical Analysis
C99H165N29O16
ANDCEQGHMPSTY
K
2017.58
12.72
7
0
8
+7
1.24
-0.213
116.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
272.60
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
15
C99H165N29O16
2017.58
12.72
+7
1.24
-0.213
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
<5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High Specific Selectivity and Membrane-Active Mechanism of Synthetic Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7. | Int J Mol Sci | 2017
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
1 %
Hemolytic
Hemolytic_activity: [Ref.28178190] 1% hemolysis at 2 µM, 5% hemolysis at 128 µM against human red cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Mol Sci. 2017 Feb 6 18(2).