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Peptide record

TPDB07909

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07909
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKTWWKTWWTKWSQP
Physicochemical Analysis
C104H141N25O21
ARNDCEGHILMFYV
W
2077.42
11.00
4
0
5
+4
-3.71
-1.873
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
1323.76
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
1
P
1
S
3
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 1 S: 1 T: 3 W: 5 Y: 0 V: 0
Chemical Descriptors
15
C104H141N25O21
2077.42
11.00
+4
-3.71
-1.873
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell selectivity and mechanism of action of short antimicrobial peptides designed from the cell-penetrating peptide Pep-1. | J Pept Sci | 2009