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Peptide record

TPDB07859

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07859
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RVKRVWPLVIRTVIA
Physicochemical Analysis
C85H148N26O17
NDCEQGHMFSY
V
1806.27
12.71
4
0
9
+4
1.09
0.720
162.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
304.49
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
1
K
0
M
0
F
1
P
0
S
1
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 4
Chemical Descriptors
15
C85H148N26O17
1806.27
12.71
+4
1.09
0.720
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>443 µM
Cytotoxic
50% Cell death | >443 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>443 µM
Hemolytic Cytotoxic
50% Hemolysis | >443 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006