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Peptide record

TPDB07852

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07852
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RNCTWLFSTKLKLPA
Physicochemical Analysis
C82H132N22O20S1
DEQGHIMYV
L
1778.15
10.59
3
0
6
+3
-1.00
-0.133
84.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
309.31
5
Residue Composition
number
1
A
1
R
1
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
3
L
2
K
0
M
1
F
1
P
1
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 2 M: 0 F: 1 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C82H132N22O20S1
1778.15
10.59
+3
-1.00
-0.133
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of the first Crocodylus siamensis cathelicidin gene and RN15 peptide derived from cathelin domain exhibiting antibacterial activity. | Biotechnol Appl Biochem | 2018
Evidence 2 Activity

Activity

<5% Killing
Toxicity
200 µg/mL
Cytotoxic
<5% Killing | 200 | µg/mL | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Identification of the first Crocodylus siamensis cathelicidin gene and RN15 peptide derived from cathelin domain exhibiting antibacterial activity. | Biotechnol Appl Biochem | 2018