Back to search

Peptide record

TPDB07796

Antibacterial Antifungal Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07796
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FKRLEKLFKKIWNWK
Physicochemical Analysis
C103H158N26O19
ADCQGHMPSTYV
K
2064.55
11.10
6
1
7
+5
0.81
-1.007
78.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
532.80
1
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
2
L
5
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
15
C103H158N26O19
2064.55
11.10
+5
0.81
-1.007
Evidence Records 2 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
15% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions. | Biochim Biophys Acta | 2008
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis