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Peptide record

TPDB07768

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07768
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
ALYKTMLKKLGTMAL
Physicochemical Analysis
C77H136N18O19S2
RNDCEQHIFPSWV
L
1682.16
10.46
3
0
9
+3
-0.72
0.520
117.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
88.58
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
3
K
2
M
0
F
0
P
0
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 3 M: 2 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
15
C77H136N18O19S2
1682.16
10.46
+3
-0.72
0.520
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and antimicrobial activity of dermaseptin S1 analogues. | Bioorg Med Chem | 2008