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Peptide record

TPDB07767

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07767
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VNWKKVLPKIIKVAK
Physicochemical Analysis
C86H150N22O17
RDCEQGHMFSTY
K
1764.27
11.12
5
0
8
+5
2.83
0.113
142.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
311.74
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
5
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
15
C86H150N22O17
1764.27
11.12
+5
2.83
0.113
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Lasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). | Chembiochem | 2009
Evidence 2 Activity

Activity

LC50
Toxicity
200 µM
Hemolytic
Hemolytic_activity: [Ref.19591185]LC50>200 µM against rat red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Chembiochem. 2009 Aug 17 10(12):2089-2105.