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Peptide record

TPDB07761

Antibacterial Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07761
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LLPALISWIKRKRQQ
Physicochemical Analysis
C86H148N26O19
NDCEGHMFTYV
L
1850.28
12.42
4
0
7
+4
1.02
-0.327
136.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
297.25
3
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
2
I
3
L
2
K
0
M
0
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 3 K: 2 M: 0 F: 0 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C86H148N26O19
1850.28
12.42
+4
1.02
-0.327
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1450 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 1450 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Individual substitution analogs of Mel(12-26), melittin's C-terminal 15-residue peptide: their antimicrobial and hemolytic actions. | FEBS Lett | 2003
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
192 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 192 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Individual substitution analogs of Mel(12-26), melittin's C-terminal 15-residue peptide: their antimicrobial and hemolytic actions. | FEBS Lett | 2003
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis