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Peptide record

TPDB07751

Antibacterial Anticancer Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07751
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WFKKIPKFLHLLKKF
Physicochemical Analysis
C103H157N23O16
ARNDCEQGMSTYV
K
1973.52
11.12
6
0
8
+5
-0.87
-0.060
104.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
278.69
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
5
K
0
M
3
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 5 M: 0 F: 3 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C103H157N23O16
1973.52
11.12
+5
-0.87
-0.060
Evidence Records 7 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
6.25 µM
Hemolytic Cytotoxic
0% Hemolysis | 6.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
1% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 3 Activity

Activity

4% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
4% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 4 Activity

Activity

8% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
8% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 5 Activity

Activity

29% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
29% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 6 Activity

Activity

IC50
Toxicity
50.0 µM
Cytotoxic
IC50 | 50.0 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 7 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis