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Peptide record

TPDB07744

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB07744
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse CAFPdb
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FKKLKKLFKKILKLK
Physicochemical Analysis
C96H171N23O16
ARNDCEQGHMPSTWYV
K
1903.56
11.36
8
0
7
+8
3.11
-0.393
130.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
8
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 8 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C96H171N23O16
1903.56
11.36
+8
3.11
-0.393
Evidence Records 2 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
4% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of Leucine and Lysine substitution on the antimicrobial activity and evaluation of the mechanism of the HPA3NT3 analog peptide. | J Pept Sci | 2009
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.19642077] 0% hemolysis at 100 µM , 3% hemolysis at 200 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2009 Sep 15(9):589-94. doi: 10.1002/psc.1155.