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Peptide record

TPDB07681

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07681
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
LKKLLKLLKKLPKL
Physicochemical Analysis
C83H158N20O15
ARNDCEQGHIMFSTWYV
L
1676.29
11.21
6
0
7
+6
2.47
0.114
195.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
7
L
6
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 7 K: 6 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C83H158N20O15
1676.29
11.21
+6
2.47
0.114
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
10% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Proline Hinged Amphipathic α-Helical Peptide Sensitizes Gram-Negative Bacteria to Various Gram-Positive Antibiotics. | J Med Chem | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis