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Peptide record

TPDB07657

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07657
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb DRAMP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GFSPNLPGKGLRIS
Physicochemical Analysis
C65H107N19O18
ADCEQHMTWYV
G
1442.68
11.49
2
0
4
+2
0.85
-0.214
83.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
2
L
1
K
0
M
1
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C65H107N19O18
1442.68
11.49
+2
0.85
-0.214
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

gainst E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 3 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 4 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

gainst E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 5 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

S.aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 6 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

gainst E-coli (MIC >50 ug/ml), S.aureus (MIC >100 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 50 ug/ml). Aslo histamine release.
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 8 Activity

Activity

0% degranulation
Toxicity
50 µg/mL
Cytotoxic
0% degranulation | 50 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007