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Peptide record

TPDB07655

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07655
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
FLLFPLMCKIQGKC
Physicochemical Analysis
C77H125N17O16S3
ARNDEHSTWYV
L
1641.12
9.11
2
0
7
+2
-1.94
1.079
111.43
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
7.62
3
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
1
Q
1
G
0
H
1
I
3
L
2
K
1
M
2
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 3 K: 2 M: 1 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C77H125N17O16S3
1641.12
9.11
+2
-1.94
1.079
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) but not active against other Gram+, N.asteroides, E.faecalis, E.faecium, Gram- E.coli ATC
Evidence 2 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) but not active against other Gram+, N.asteroides, E.faecalis, E.faecium, Gram- E.coli ATC
Evidence 3 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) but not active against other Gram+, N.asteroides, E.faecalis, E.faecium, Gram- E.coli ATC
Evidence 4 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 37.5 ug/ml) but not active against other Gram+, N.asteroides, E.faecalis, E.faecium, Gram- E.coli ATC
Evidence 5 Activity

Activity

2% Hemolysis
Toxicity
80 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 80 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri. | Biochimie | 2010
Evidence 6 Activity

Activity

26.3% degranulation
Toxicity
200 µg/mL
Cytotoxic
26.3% degranulation | 200 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri. | Biochimie | 2010