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Peptide record

TPDB07654

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07654
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AILTTLANWARKFL
Physicochemical Analysis
C77H124N20O18
DCEQGHMPSYV
AL
1617.95
11.49
2
0
9
+2
-2.98
0.707
132.86
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
339.94
3
Residue Composition
number
3
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
1
K
0
M
1
F
0
P
0
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 1 M: 0 F: 1 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C77H124N20O18
1617.95
11.49
+2
-2.98
0.707
Evidence Records 23 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

S. carnosus KHS

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faeca
Evidence 3 Activity

Activity

MIC
Antibacterial
4.8 µM

Target

R. rhodochrous X15

Source & Reference

dbAMP DRAMP

Other

s ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATC
Evidence 4 Activity

Activity

MIC
Antibacterial
75 µM

Target

P. faecalis X29

Source & Reference

dbAMP DRAMP

Other

37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
19-75 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
37.5 µM

Target

S. carnosus KHS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faeca
Evidence 8 Activity

Activity

MIC
Antifungal
4.8 µM

Target

R. rhodochrous X15

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

s ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATC
Evidence 9 Activity

Activity

MIC
Antifungal
75 µM

Target

P. faecalis X29

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
19-75 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
37.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC
Evidence 12 Activity

Activity

MIC
Antiparasitic
37.5 µM

Target

S. carnosus KHS

Source & Reference

DRAMP

Other

Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faeca
Evidence 13 Activity

Activity

MIC
Antiparasitic
4.8 µM

Target

R. rhodochrous X15

Source & Reference

DRAMP

Other

s ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATC
Evidence 14 Activity

Activity

MIC
Antiparasitic
75 µM

Target

P. faecalis X29

Source & Reference

DRAMP

Other

37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
19-75 µM

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 16 Activity

Activity

MIC
Antiviral
37.5 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC
Evidence 17 Activity

Activity

MIC
Antiviral
37.5 µM

Target

S. carnosus KHS

Source & Reference

DRAMP

Other

Active against S. aureus ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faeca
Evidence 18 Activity

Activity

MIC
Antiviral
4.8 µM

Target

R. rhodochrous X15

Source & Reference

DRAMP

Other

s ATCC2592 (MIC 37.5 uM), S. carnosus KHS (MIC 37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATC
Evidence 19 Activity

Activity

MIC
Antiviral
75 µM

Target

P. faecalis X29

Source & Reference

DRAMP

Other

37.5 uM), B. licheniformis X39 (MIC 19 u), R. rhodochrous X15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 20 Activity

Activity

MIC
Antiviral
19-75 µM

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

15 (MIC 4.8 uM) Gram-negative P. faecalis X29 (MIC 75 uM), and fungi S. mould 090223 and C. albicans ATCC2002 (MIC 19-75 uM).
Evidence 21 Activity

Activity

50% Hemolysis
Toxicity
75 µM
Hemolytic Cytotoxic
50% Hemolysis | 75 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis. | Peptides | 2012
Evidence 22 Activity

Activity

10.5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
10.5% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host defense peptides in skin secretions of Odorrana tiannanensis: Proof for other survival strategy of the frog than merely anti-microbial. | Biochimie | 2012
Evidence 23 Activity

Activity

IC50
Toxicity
75 µM
Hemolytic
Hemolytic_activity: [Ref:22450466]IC50=75 µM against washed human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2012 Jun 35(2):285-290.