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Peptide record

TPDB07650

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07650
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
NFLDTLINLAKKFI
Physicochemical Analysis
C79H128N18O20
RCEQGHMPSWYV
L
1649.99
9.88
2
1
8
+1
-0.54
0.629
146.43
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
2
N
1
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
2
K
0
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 2 M: 0 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C79H128N18O20
1649.99
9.88
+1
-0.54
0.629
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus (MIC 50 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus (MIC 50 uM).
Evidence 3 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus (MIC 50 uM).
Evidence 4 Activity

Activity

MIC
Antiviral
50 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against S. aureus (MIC 50 uM).
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
50% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis. | Dev Comp Immunol | 2011