Back to search

Peptide record

TPDB07643

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07643
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWKKIFEKVKNLV
Physicochemical Analysis
C85H139N21O19
ARDCQGHMPSTY
K
1759.17
10.55
4
1
7
+3
2.80
-0.214
125.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
312.65
2
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
1
E
0
Q
0
G
0
H
2
I
1
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
14
C85H139N21O19
1759.17
10.55
+3
2.80
-0.214
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and
Evidence 2 Activity

Activity

MIC
Antibacterial
11.8 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM)
Evidence 3 Activity

Activity

MIC
Antibacterial
50-150 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
7.5 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and
Evidence 5 Activity

Activity

MIC
Antifungal
11.8 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM)
Evidence 6 Activity

Activity

MIC
Antifungal
50-150 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP Antifungipept

Other

and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
7.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and
Evidence 8 Activity

Activity

MIC
Antiparasitic
11.8 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM)
Evidence 9 Activity

Activity

MIC
Antiparasitic
50-150 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM).
Evidence 10 Activity

Activity

MIC
Antiviral
7.5 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and
Evidence 11 Activity

Activity

MIC
Antiviral
11.8 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against E. coli (MIC 7.5 uM) and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM)
Evidence 12 Activity

Activity

MIC
Antiviral
50-150 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

and B. subtilis (MIC 11.8 uM). Also active against S. aureus (similar to B. subtilis) and P. aeruginosa (MIC 50-150 uM).
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs | Peptides | 2008
Evidence 14 Activity

Activity

IC50
Toxicity
100 µM
Hemolytic
Hemolytic_activity: [Ref.18375018]IC50>100 µM against rat red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2008 Jun 29(6):992-1003.