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Peptide record

TPDB07641

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07641
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI PD_Hemolysis ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GRILSFIKGLAEHL
Physicochemical Analysis
C72H120N20O18
NDCQMPTWYV
L
1553.87
10.09
3
1
7
+1
1.33
0.593
146.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
0
Q
2
G
1
H
2
I
3
L
1
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 2 L: 3 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C72H120N20O18
1553.87
10.09
+1
1.33
0.593
Evidence Records 5 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
42 %
[Ref.18695936]42% hemolytic activity at 50 µM against sheep blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

40% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
40% Hemolysis | 50 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni. | Amino Acids | 2009
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Venom peptides from solitary hunting wasps induce feeding disorder in lepidopteran larvae. | Peptides | 2011
Evidence 4 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.18695936]42% hemolytic activity at 50 µM against sheep blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.
Evidence 5 Hemolysis

Activity

42 %
% Hemolysis
[Ref.18695936]42% hemolytic activity at 50 µM against sheep blood cells
Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
Toxicon. 2010 Apr 1 55(4):711-718.##Amino Acids. 2009 Jul 37(2):389-394.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.