Back to search

Peptide record

TPDB07636

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07636
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWLKAKKVAGMIL
Physicochemical Analysis
C75H129N19O16S1
RDCEQHFPSTY
K
1585.03
10.84
3
0
9
+3
-0.69
0.700
146.43
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
347.00
1
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C75H129N19O16S1
1585.03
10.84
+3
-0.69
0.700
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
23.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 23.4 ug/ml), P.aeruginosa (MIC 125 ug/ml), S. aureus (MIC 42.9 ug/ml), and B. subtilis (MIC 11.7 ug/m
Evidence 2 Activity

Activity

MIC
Antibacterial
125 µg/mL

Target

P.aeruginosa

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 23.4 ug/ml), P.aeruginosa (MIC 125 ug/ml), S. aureus (MIC 42.9 ug/ml), and B. subtilis (MIC 11.7 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
42.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 23.4 ug/ml), P.aeruginosa (MIC 125 ug/ml), S. aureus (MIC 42.9 ug/ml), and B. subtilis (MIC 11.7 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
11.7 µg/mL

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

t E. coli (MIC 23.4 ug/ml), P.aeruginosa (MIC 125 ug/ml), S. aureus (MIC 42.9 ug/ml), and B. subtilis (MIC 11.7 ug/ml).
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Investigating the effect of different positioning of lysine residues along the peptide chain of mastoparans for their secondary structures and biological activities | Amino Acids | 2011
Evidence 6 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Rat peritoneal mast cells

Target

Rat peritoneal mast cells

Source & Reference

NA
DBAASP
Structure-activity relationship of mastoparan analogs: Effects of the number and positioning of Lys residues on secondary structure, interaction with membrane-mimetic systems and biological activity. | Peptides | 2015