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Peptide record

TPDB07612

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07612
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
INLKAIAALVKKLL
Physicochemical Analysis
C72H134N18O16
RDCEQGHMFPSTWY
L
1507.97
10.84
3
0
10
+3
0.09
1.329
209.29
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C72H134N18O16
1507.97
10.84
+3
0.09
1.329
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 20 uM), E. faecalis ATCC29212 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 2
Evidence 2 Activity

Activity

MIC
Antibacterial
80 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 20 uM), E. faecalis ATCC29212 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC259
Evidence 3 Activity

Activity

MIC
Antibacterial
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP

Other

12 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMC
Evidence 4 Activity

Activity

MIC
Antibacterial
80 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP

Other

(MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginos
Evidence 5 Activity

Activity

MIC
Antibacterial
40 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP

Other

C 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteria
Evidence 6 Activity

Activity

MIC
Antibacterial
40 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

(MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 40 uM), E.coli IS 117# (MIC >160 uM), E.
Evidence 7 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. dysenteriae

Source & Reference

dbAMP

Other

3 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 40 uM), E.coli IS 117# (MIC >160 uM), E. coli IS 218# (MIC 80 uM), P
Evidence 8 Activity

Activity

MIC
Antibacterial
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

(MIC 80 uM), P. aeruginosa IS 350# (MIC 40 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/
Evidence 9 Activity

Activity

MIC
Antibacterial
80 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP

Other

# (MIC 40 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antibacterial
40 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP

Other

>160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 11 Activity

Activity

MIC
Antifungal
20 µM

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive S. aureus ATCC25923 (MIC 20 uM), E. faecalis ATCC29212 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 2
Evidence 12 Activity

Activity

MIC
Antifungal
80 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram-positive S. aureus ATCC25923 (MIC 20 uM), E. faecalis ATCC29212 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC259
Evidence 13 Activity

Activity

MIC
Antifungal
>160 µM

Target

E.coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

12 (MIC 80 uM), S. aureus IS 10# (MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMC
Evidence 14 Activity

Activity

MIC
Antifungal
80 µM

Target

Enterobacter cloacae ATCC13047

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), S. aureus IS 37# (MIC 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginos
Evidence 15 Activity

Activity

MIC
Antifungal
40 µM

Target

Klebsiella pneumoniae ATCC700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 20 uM), Gram-negative E.coli ATCC25922 (MIC >160 uM), E. cloacae ATCC13047 (MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteria
Evidence 16 Activity

Activity

MIC
Antifungal
40 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), K. pneumoniae ATCC700603 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 40 uM), E.coli IS 117# (MIC >160 uM), E.
Evidence 17 Activity

Activity

MIC
Antifungal
20 µM

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

3 (MIC 40 uM), B pyocyaneus CMCCB1010 (MIC >160 uM), P. aeruginosa ATCC27853 (MIC 40 uM), B. dysenteriae (MIC 20 uM), E. coli IS 37# (MIC 40 uM), E.coli IS 117# (MIC >160 uM), E. coli IS 218# (MIC 80 uM), P
Evidence 18 Activity

Activity

MIC
Antifungal
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), P. aeruginosa IS 350# (MIC 40 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/
Evidence 19 Activity

Activity

MIC
Antifungal
80 µM

Target

Candida albicans ATCC90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

# (MIC 40 uM), K.pneumoniae IS 59# (MIC >160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 20 Activity

Activity

MIC
Antifungal
40 µM

Target

C. parapsilosis ATCC22019

Source & Reference

dbAMP CAFPdb Antifungipept

Other

>160 uM), fungi C. albicans ATCC2002 (MIC 80 uM), C. albicans ATCC90028 (MIC 80 uM), and C. parapsilosis ATCC22019 (MIC 40 uM). Updated 7/2021
Evidence 21 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the venom gland of the social wasp Vespa tropica. | Toxicon | 2013