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Peptide record

TPDB07601

Antibacterial Antifungal Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07601
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFWGKLWEGVKSAI
Physicochemical Analysis
C77H112N18O18
RNDCQHMPTY
G
1577.85
9.88
2
1
7
+1
-1.64
0.143
83.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
697.15
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
0
H
1
I
1
L
2
K
0
M
1
F
0
P
1
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
14
C77H112N18O18
1577.85
9.88
+1
-1.64
0.143
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
80.3 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 80.3 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
StCT2, a new antibacterial peptide characterized from the venom of the scorpion Scorpiops tibetanus. | Peptides | 2012
Evidence 2 Activity

Activity

EC50
Toxicity
63.68 µM
Cytotoxic
EC50 | 63.68 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
70.48 µM
Hemolytic Cytotoxic
10% Hemolysis | 70.48 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
126.2 µM
Hemolytic Cytotoxic
50% Hemolysis | 126.2 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 5 Activity

Activity

90% Hemolysis
Toxicity
246.84 µM
Hemolytic Cytotoxic
90% Hemolysis | 246.84 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 6 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.