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Peptide record

TPDB07584

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07584
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
LKLKSIVSWAKAVL
Physicochemical Analysis
C75H130N18O17
RNDCEQGHMFPTY
LK
1555.97
10.84
3
0
9
+3
-0.81
0.979
167.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
353.48
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
3
K
0
M
0
F
0
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 3 M: 0 F: 0 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
14
C75H130N18O17
1555.97
10.84
+3
-0.81
0.979
Evidence Records 3 records
Evidence 1 Activity

Activity

59% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
59% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Relationship between the tertiary structures of mastoparan B and its analogs and their lytic activities studied by NMR spectroscopy. | J Pept Res | 2000
Evidence 2 Activity

Activity

66% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
66% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Relationship between the tertiary structures of mastoparan B and its analogs and their lytic activities studied by NMR spectroscopy. | J Pept Res | 2000
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis