Back to search

Peptide record

TPDB07570

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB07570
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FIGALLRPALKLLA
Physicochemical Analysis
C73H126N18O15
NDCEQHMSTWYV
L
1495.91
11.49
2
0
10
+2
-2.49
1.521
188.57
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
5
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C73H126N18O15
1495.91
11.49
+2
-2.49
1.521
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
0% Hemolysis | 20 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Identification of novel peptides from amphibian (Xenopus tropicalis) skin by direct tissue MALDI-MS analysis. | FEBS J | 2015
Evidence 2 Activity

Activity

2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
2% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin. | J Biochem | 2016
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
0.4 %
Hemolytic
Hemolytic_activity: [Ref.25312021]0.4% Hemolysis against Rat erythrocytes at 20 µM.##[Ref.26802742]2% Hemolysis against Rat erythrocytes at 50 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
FEBS J. 2015 Jan 282(1):102-13.##J Biochem. 2016 Jun 159(6):619-29.