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Peptide record

TPDB07557

Antibacterial Antifungal standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07557
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IIYCNRRTGKCQRM
Physicochemical Analysis
C71H124N26O19S3
ADEHLFPSWV
R
1742.11
10.42
4
0
4
+4
2.30
-0.779
55.71
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1615
92.70
6
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
1
G
0
H
2
I
0
L
1
K
1
M
0
F
0
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 0 K: 1 M: 1 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C71H124N26O19S3
1742.11
10.42
+4
2.30
-0.779
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.2-2.5 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus
Evidence 2 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidola
Evidence 3 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidolactici (MIC >40 uM), Gram- E. c
Evidence 4 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

Escherichia coli D22 or D31

Source & Reference

dbAMP DRAMP

Other

uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidolactici (MIC >40 uM), Gram- E. coli D22 or D31 (MIC 20-40 uM) strain 106 >40 uM, S-typhimurium (MIC >40 uM), K. pneumoniae (MIC 20-40 uM), E-cloacae (M
Evidence 5 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

), Gram- E. coli D22 or D31 (MIC 20-40 uM) strain 106 >40 uM, S-typhimurium (MIC >40 uM), K. pneumoniae (MIC 20-40 uM), E-cloacae (MIC >40 uM), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. c
Evidence 6 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP

Other

uM), E-cloacae (MIC >40 uM), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. crassa (MIC 20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassi
Evidence 7 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP

Other

M), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. crassa (MIC 20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culm
Evidence 8 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

A. brassicola

Source & Reference

dbAMP DRAMP

Other

20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culmorum (MIC 20-40 uM), A-pisi (MIC >40 uM), and F-oxysporum (MIC >40 uM).
Evidence 9 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

F. culmorum

Source & Reference

dbAMP DRAMP

Other

-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culmorum (MIC 20-40 uM), A-pisi (MIC >40 uM), and F-oxysporum (MIC >40 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
1.2-2.5 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus
Evidence 11 Activity

Activity

MIC
Antifungal
5-10 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidola
Evidence 12 Activity

Activity

MIC
Antifungal
10-20 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against Gram+ A. viridans (MIC 1.2-2.5 uM), M. luteus (MIC 5-10 uM), B. megaterium (MIC 10-20 uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidolactici (MIC >40 uM), Gram- E. c
Evidence 13 Activity

Activity

MIC
Antifungal
20-40 µM

Target

Escherichia coli D22 or D31

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), B-subtilis (MIC >40 uM), S-aureus (MIC > 40 uM), P-acidolactici (MIC >40 uM), Gram- E. coli D22 or D31 (MIC 20-40 uM) strain 106 >40 uM, S-typhimurium (MIC >40 uM), K. pneumoniae (MIC 20-40 uM), E-cloacae (M
Evidence 14 Activity

Activity

MIC
Antifungal
20-40 µM

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), Gram- E. coli D22 or D31 (MIC 20-40 uM) strain 106 >40 uM, S-typhimurium (MIC >40 uM), K. pneumoniae (MIC 20-40 uM), E-cloacae (MIC >40 uM), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. c
Evidence 15 Activity

Activity

MIC
Antifungal
20-40 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), E-cloacae (MIC >40 uM), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. crassa (MIC 20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassi
Evidence 16 Activity

Activity

MIC
Antifungal
10-20 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

M), E-carotovora (MIC >40 uM), P-aeruginosa (MIC >40 uM), fungi N. crassa (MIC 20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culm
Evidence 17 Activity

Activity

MIC
Antifungal
5-10 µM

Target

A. brassicola

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

20-40 uM), B. cinerea (MIC 10-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culmorum (MIC 20-40 uM), A-pisi (MIC >40 uM), and F-oxysporum (MIC >40 uM).
Evidence 18 Activity

Activity

MIC
Antifungal
20-40 µM

Target

F. culmorum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

-20 uM), N-haematococca (MIC >40 uM), T-viride (MIC >40 uM), A. brassicola (MIC 5-10 uM), F. culmorum (MIC 20-40 uM), A-pisi (MIC >40 uM), and F-oxysporum (MIC >40 uM).