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Peptide record

TPDB07551

Antibacterial Antifungal Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07551
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
CLLKKLLKKLLKKC
Physicochemical Analysis
C78H150N20O15S2
ARNDEQGHIMFPSTWYV
LK
1672.29
10.54
6
0
6
+6
2.10
0.314
167.14
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
7.47
2
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C78H150N20O15S2
1672.29
10.54
+6
2.10
0.314
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
82 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 82 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
The effect of thiol functional group incorporation into cationic helical peptides on antimicrobial activities and spectra. | Biomaterials | 2011
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis