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Peptide record

TPDB07543

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07543
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AKLWLKAAKLWLKA
Physicochemical Analysis
C82H134N20O15
RNDCEQGHIMFPSTYV
ALK
1640.09
11.00
4
0
10
+4
-2.66
0.357
140.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
11000
670.69
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
14
C82H134N20O15
1640.09
11.00
+4
-2.66
0.357
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric ?-helical peptides with Gly-Gly pairs. | Sci Rep | 2015