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Peptide record

TPDB07524

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07524
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GVVVRVGRVVVRWV
Physicochemical Analysis
C73H126N24O15
ANDCEQHILKMFPSTY
V
1579.96
12.70
3
0
9
+3
1.16
1.314
165.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
348.11
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 8
Chemical Descriptors
14
C73H126N24O15
1579.96
12.70
+3
1.16
1.314
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
43 µM
Hemolytic Cytotoxic
50% Hemolysis | 43 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of Val/Arg-rich peptides: effects of net charge and pro on activity. | Chem Biol Drug Des | 2014
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis