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Peptide record

TPDB07514

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB07514
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFWGKLLEGVKKAI
Physicochemical Analysis
C75H120N18O17
RNDCQHMPSTY
GK
1545.89
10.32
3
1
7
+2
0.51
0.257
111.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
355.78
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
0
H
1
I
2
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C75H120N18O17
1545.89
10.32
+2
0.51
0.257
Evidence Records 4 records
Evidence 1 Activity

Activity

EC50
Toxicity
67.63 µM
Cytotoxic
EC50 | 67.63 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
110.86 µM
Hemolytic Cytotoxic
10% Hemolysis | 110.86 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
1636 µM
Hemolytic Cytotoxic
50% Hemolysis | 1636 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
24141.72 µM
Hemolytic Cytotoxic
90% Hemolysis | 24141.72 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017